Table 2 Example of the overrepresentation test for the case where a drug has 5 targets distributed across several CATH-FunFams.

From: Structural and Functional View of Polypharmacology

FunFam

\({{\boldsymbol{n}}}_{{\boldsymbol{FF}}}\)

P FF

success

trials

Overrep. threshold

p-val

FF1

6

0.24

1

5

1.2

1

FF2

3

0.12

2

5

0.6

0.113

FF3

7

0.28

1

5

1.4

1

FF4

9

0.36

1

5

1.8

0.66

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