Figure 1
From: Structure-based drug discovery for combating influenza virus by targeting the PA–PB1 interaction
Hit compounds with anti-influenza virus activity. Hit compounds selected by in silico screening were tested to determine their anti-influenza virus activities via cell-based screening. Potent compounds with anti-influenza virus activities (MIC value < 20 μM) are shown. (a) Compounds bearing quinolinone and tetrazole moieties. (b) Compounds containing different scaffolds.
