Figure 1 | Scientific Reports

Figure 1

From: Urokinase-type plasminogen activator receptor (uPAR) expression enhances invasion and metastasis in RAS mutated tumors

Figure 1

uPAR expression and functions in NSCLC and CRC cells, characterized by different RAS mutational status. (A,B) Western blot and cytofluorimetric analysis of uPAR expression in three NSCLC cell lines (PC9, H460, H1299) and in three CRC cell lines (SW48, HCT116, SW480). All immunoblot bands are cropped, full-length blot images are provided in Supplementary Figure S5. (C,D) Percent of adhesion and migration to VN in NSCLC and in CRC cell lines. Data represent the mean (±SD) of three independent experiments, each performed in triplicate. Asterisks indicate statistical significance of analyzed cellular processes in RAS mutated compared with RAS wild-type cell lines considered as 100%, determined by the Student t-test (**P < 0.005; ***P < 0.001).

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