Table 2 Relationship between mutations in the QRDR regions of the gyrA gene and the MICs for 21 C. striatum classified as resistant or intermediate to fluoroquinolones.
Number of strains | Ciprofloxacin | Moxifloxacin | ||||
|---|---|---|---|---|---|---|
MIC (mg/L) | Phenotype | MIC (mg/L) | Phenotype | Ser-87 | Asp-91 | |
8 | >16 | R | >16 | R | Phe | Gly |
3 | >16 | R | >16 | R | Phe | Ala |
1 | >16 | R | 8 | R | Phe | Gly |
1 | >16 | R | 8 | R | Phe | Ala |
1 | >16 | R | 4 | R | Ala | Gly |
1 | 8 | R | 1 | I | Phe | Asp |
2 | 4 | R | 1 | I | Tyr | Asp |
2 | 2 | I | 1 | I | Ser | Gly |
1 | 8 | R | 1 | I | Ser | Asp |
1 | 4 | R | 1 | I | Ser | Asp |
