Figure 6

In silico predicted interactions between significantly up-regulated mRNAs (red) and down-regulated microRNAs (green) in LH+8 vs. LH+2 endometrium. The colour intensity indicates the strength of up- or down-regulation (FDR < 0.05). The colour of the arrows between the microRNA and mRNA represents TargetScan context++ score (see Supplementary Table 2 for scores), where darker arrow shows more probable interaction. The number of arrows between microRNA and mRNA indicates different microRNA binding sites within the same transcript. Meta-signature genes that were confirmed in both independent validation analyses together with their corresponding miRNAs are highlighted with black circle/diamond borders.