Figure 6 | Scientific Reports

Figure 6

From: Potential therapeutic targets for ALS: MIR206, MIR208b and MIR499 are modulated during disease progression in the skeletal muscle of patients

Figure 6

Histological analysis of ALS patients. (A) Representative images that showed the pattern of muscle fibre atrophy, with different fibre types stained differently. Differences in the fibre type ratio is detected between ALS patients in the slow group (left panels) and those in the rapid group (right panels). The hematoxylin-eosin staining (top panels) and the ATPase staining (bottom panels) highlighted the atrophy pattern and fibre composition. (B) The bar-graph illustrates the percentage of type I, type II and atrophic fibres in the skeletal muscle sections of rapid and slow ALS patients. An overall number of >1000 muscle fibres was counted for each assessed patient.

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