Figure 3 | Scientific Reports

Figure 3

From: Metabotropic glutamate receptor 5 deficiency inhibits neutrophil infiltration after traumatic brain injury in mice

Figure 3

Knockout of mGluR5 reduces BBB permeability. (A) 24 h after TBI, the leakage of Evans blue was identified in brain sections at 2 h after injection. Area and mean density analysis are presented. Data are represented as the mean ± standard error of the mean (*P < 0.05). (B) Representative immunofluorescence images of tight junction protein claudin-5 localized at the periphery of vWF-positive endothelial cells. Nuclei were stained with DAPI.

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