Figure 3 | Scientific Reports

Figure 3

From: Emergence of Alternative Structures in Amyloid Beta 1-42 Monomeric Landscape by N-terminal Hexapeptide Amyloid Inhibitors

Figure 3

Characterization of Aβ42 tertiary structure. (a) Ensemble-averaged intramolecular Cα contact map of the free Aβ42 monomer42 (upper triangle). Only non-sequential contacts, i.e., |i–j| ≥ 3, are considered. Arithmetic difference between the contact probabilities of hexapeptide-bound and free Aβ42 are also plotted (a, lower triangle: WT-bound; b, upper triangle: A2V-bound; b, lower triangle: A2T-bound). Color-scales used for contact probability and contact probability differences (bound minus free) are shown on top of the figures.

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