Figure 2

Expression profile of REST in the prefrontal cortex (superior frontal gyrus) and cerebellar cortex at different age points. Data are derived by Somel et al.23 and refer to humans (red), macaques (black), and chimpanzees (blue). Each point represents an individual (25 humans, 31 macaques, and 12 chimpanzees) and lines show lowess fittings47. Lighter lines represent the 2.5 and 97.5 confidence intervals calculated using 1000 bootstrap replicates. Age (x-axis) is reported in log2 scale and REST expression level in log scale.