Figure 1 | Scientific Reports

Figure 1

From: TCR–like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus–transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants

Figure 1

HLA-A*02 frequencies, distribution and alleles. (A) Frequencies of nine HLA-A loci within the European, North American, Northeast Asian and Southeast Asian populations. (B) HLA-A*02:01, A*02:03, A*02:06 and A*02:07 frequencies and distribution among the four populations. Alleles with frequencies of more than 5% from any of the four populations were illustrated. Values were extracted from the NCBI dbMHC database (http://www.ncbi.nlm.nih.gov/gv/mhc/). (C) Polymorphic amino acid residue changes between A*02:01, A*02:03, A*02:06 and A*02:07 found in the α1 and α2 domains of the MHC class molecule. (D) Top and side structural depiction of the four HLA-A*02 alleles, with peptide binding pockets highlighted and polymorphic residues indicated in red.

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