Figure 1 | Scientific Reports

Figure 1

From: Aggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis

Figure 1

Expression of mPGES-2 in LPS-induce acute kidney injury mouse model. (A) Shown are the levels of serum urea nitrogen and creatinine measured at different time points. (B) Shown are the degrees of kidney injury and injury scores in mice at different time points after LPS treatment. Scale bar: 50 μm. (C) Shown are the expressions of mPGES-2 and LC-3B in kidney of mice with LPS-induce AKI. The histogram below shows the gray scale ratio of mPGES-2 to β-actin and LC3B-II/LC3B-I. (D) Shown are distributions of mPGES-2 in renal cortex (upper panel) and medulla (lower panel) of mice with LPS-induced AKI. Scale = 50 μm. *P < 0.05 versus the control group. Data are mean ± SD. (n = 6).

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