Figure 4
Hepatic gene expression in mice on MR (n = 9–10), LR (n = 8–10) and control (n = 7–9) diet. qPCR was used to measure gene expression in the liver of (a) lipogenic genes (b) lipolytic and oxidative genes (c) gluconeogenic genes and (d) FGF21 and ATF4 in mice fed MR, LR or control diet. Data were analysed as fold change relative to control-fed mice. Significance was calculated by two-tailed Student’s t-test. a,bMeans with letters that differ denote significance at level of P < 0.05. Data are represented as mean ± SEM. White bars, control-fed mice; grey bars, LR-fed mice; black bars, MR-fed mice.
