Figure 2

Changes observed in red blood cells and formation of bacteria-like forms in incubated human blood. Aliquots of human blood were incubated at 30 °C for seven days and observed under dark-field microscopy without fixation or staining. (A) Aggregated RBCs; (B) RBC with spicules (arrow); (C) particles inside RBC (arrows); (D) filamentous cell debris; (E) RBC vesiculation with spicules or tubule formations (arrow); (F) membrane structures; (G,H) elongated bacteria-like forms (arrow in G); (I) intracellular vesicles; (J) coccoid-like vesicles (arrow); (K) bacteria-like forms (arrow); (L) bacteria-like structures similar to cells undergoing division. Scale bars: 8 μm.