Figure 2
From: Predicting synonymous codon usage and optimizing the heterologous gene for expression in E. coli
The entropy of the codon usage pattern of the middle amino acid with the different amino acid neighbors in E. coli. The x-axis represents the different number of the adjacent amino acids. The y-axis represents the average entropy of all codon usage pattern of the middle amino acid with corresponding adjacent amino acids. The data were calculated by the 65 genomes of E. coli (Table S1).
