Figure 2 | Scientific Reports

Figure 2

From: Increased incidence of cytomegalovirus coinfection in HCV-infected patients with late liver fibrosis is associated with dysregulation of JAK-STAT pathway

Figure 2

The transcriptional levels of JAK-STAT pathway mediators in CMV positive versus CMV negative chronic HCV-infected patients. qRT-PCR was employed to quantify the mRNA abundance of IFNAR1 (a), IFNAR2 (b), TYK2 (c), JAK1 (d), IRF9 (e), STAT1 (f), STAT2 (g), and IRF7 (h) in PBMCs of control group (CMV− HCV−, n = 15), CMV mono-infected patients (CMV+ HCV−, n = 4), and HCV-infected patients with positive CMV DNAemia (HCV+ CMV+ , n = 39) and with negative CMV DNAemia (HCV+ CMV−, n = 51). The house keeping gene B2M was used for data normalization. The relative gene expression of each transcript was presented as fold change comparative to the mean of control group. (*p < 0.05; **p < 0.01).

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