Table 5 Docking scores and calculatedΔG of designed compounds.

From: New molecular insights into the tyrosyl-tRNA synthase inhibitors: CoMFA, CoMSIA analyses and molecular docking studies

Molecule

Docking score

ΔG (kcal · mol−1)

D1

6.4131

−19.4

D2

8.0254

−32.4

D3

6.8264

−29.9

D4

7.5216

−30.2

D5

7.1824

−24.7

D6

6.3483

−22.1

D7

8.4677

−34.5

D8

7.1582

−21.1

D9

6.9573

−27.8

D10

7.0564

−19.4

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