Figure 3
Concurrent microscopic parasitemia associated with diminished Vδ2+ T cell counts and cytokine production following in vitro stimulation. (A) Absolute CD3+ Vδ2+ cells/μl among uninfected, submicroscopically infected, microscopically infected/asymptomatic, and microscopically infected/symptomatic children living in high transmission setting. (B) Association between absolute CD3+ Vδ2+ cells/μl and parasite densities among infected children (submicroscopically infected children have parasite density estimated at 10 parasites/μl). Shown is 95% confidence interval of best fit regression line. (C) Percentage of Vδ2+ cells among total CD3+ and (D) Percentage of Vδ2+ T cells producing cytokines following in vitro stimulation with P. Falciparum infected red blood cells among uninfected, submicroscopically infected, and microscopically infected/asymptomatic children living in high transmission setting. Rs: Spearman correlation. Between group comparisons made with Wilcoxon ranksum test. Median indicated by black bar.
