Figure 2

Glucose metabolism in 60-hour fasted rats born to DEX-treated mothers. (A) Blood glucose levels were determined at different time points in CTL (rats born to untreated mothers) and DEX (rats born to DEX-treated mothers) rats during a 72-hour fasting period. (B) GTT, (C) ITT and (D) PTT were performed in 60-hour fasted CTL and DEX rats. The AUCs were calculated for glucose tests and PTTs. The KITT was calculated for ITTs. (E) Hepatic determination of pck1 and gcpc mRNA was normalized to rpl37a expression (F) Hepatic determination of PEPCK and G6Pase was normalized to β actin. (G) Circulating insulin was assessed at specific time points during the GTT. Data are shown as the mean ± S.E.M.; *p < 0.05 vs. CTL.