Figure 2
From: Serum lysophospholipid levels are altered in dyslipidemic hamsters
Circulating levels of different enzymes involved in Lyso-PL synthesis in hamsters with different degrees of dyslipidemia. The animals were distributed into three groups: C, group fed a normal-fat diet (NFD); HFD, group fed a high-fat diet; and P407, group fed an NFD and periodically injected with the pro-dyslipidemic agent P407. Half of the animals in each group were sacrificed on day 4 (4d) and the other half were sacrificed on day 30 (30d). The dose of P407 was 50 mg/kg every 3 days. Non-P407 hamsters received injections of vehicle (0.9% NaCl) with equal periodicity. All animals were sacrificed 24 h after the last administration of P407 or vehicle and after a 6 h fast. The concentrations of serum parameters were determined at the end of the experiment. The data are presented as means ± SEM (n = 9–10). The statistical comparisons among groups were conducted using two- and one-way ANOVAs. I: the effect of the pro-dyslipidemic intervention (HFD and P407); t: the effect of time (two-way ANOVA, p < 0.05). In each figure, different superscript lowercase letters (a,b,c) indicate significant different mean values (one-way ANOVA and Tukey’s or Games-Howell post hoc tests, p < 0.05).
