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Figure 1

From: Interleukin-6-dependent growth in a newly established plasmablastic lymphoma cell line and its therapeutic targets

Figure 1

Morphology of PBL-1. (a) Microscopic view of PBL-1. Giemsa staining of original tumour cells in the ascites of an HIV positive PBL patient (upper panel) and PBL-1 (middle panel), and EBER-1 in situ hybridization on a formalin-fixed paraffin-embedded sample of a PBL-1 cell pellet (lower panel) are shown. Each black bar indicates 10 μm. EBV-positive lymphoma tissues from other unrelated patients also showed positive signals in EBER-1 in situ hybridization (data not shown). (b) Transmission electron microscopy of PBL-1. Chromatin concentrated in the centre and margin of the nucleus, with a wheel-like appearance (upper panel). Abundant rough endoplasmic reticulum is observed in the perinuclear region (lower panel).

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