Table 5 Comparing the miRNA profiling data with other NPC publications.
From: MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma
miRNAs | Dataset from this study | Dataset from Li (Li et al., 2011) | Dataset from Chen (Chen et al., 2009) | Dataset from Sengupta (Sengupta et al., 2008) |
|---|---|---|---|---|
205 | ↑ (13.0) | X | ↑ (4.0) | — (0.99) |
196a | ↑ (12.9) | X | ND | ↓ (0.62) |
149 | ↑ (6.8) | X | ND | — (0.95) |
183 | ↑ (6.0) | X | ND | ↑ (2.06) |
224 | ↑ (5.7) | X | ND | ↑ (4.1) |
210 | ↑ (5.0) | ↓ (−14.27) | ND | — (1.0) |
136 | ↑ (4.8) | X | ND | ↑ (1.7) |
200c | ↑ (4.1) | X | ND | — (1.0) |
141 | ↑ (3.5) | X | ND | — (1.2) |
150 | ↓ (−5.3) | ↓ (−4.47) | ND | ↑ (1.52) |
Study groups | 17 NPC /7 biopsy-negative FFPE tissues | 8 NPC/ 4 normal donors snap-frozen NP tissues | 13 NPC snap-frozen tissues / 9 paired adjacent normal NP tissues from patients | 31 NPC samples/ 10 normal NP tissues (from 2 normal donors, 4 biopsy-negative tissues, 4 paired adjacent normal NP tissues) |
NPC Staging | II, III, IV | II, III, IV | Unknown | II |
Differentiation | Undifferentiated | Poorly differentiation | Unknown | Unknown |
Origin | Hong Kong | Guangxi province of China | Taiwan | Taiwan |
Test method | Whole tissue/ Real time PCR | Whole tissue/ miRNA microarray | Whole tissue/ Real time PCR | Laser-capture microdissection /miRNA microarray |
Deregulation cut-off fold change | ± 3 folds | q-value ≤ 0.05 | ± 3 folds | ± 1.5 folds |
