Table 2 Calculation of sensitivities and specificities from expert MRI and EEG analysis, see TableĀ S2 of the SI for details.

From: Personalized structural image analysis in patients with temporal lobe epilepsy

MRI dataset

patient

morphometry: sensitivity

morphometry: specificity

agreement

vs. expert MRI

vs. surgery

vs. EEG

vs. expert MRI

vs. surgery

vs. EEG

expert MRI vs. EEG

MTLE-HS left

P001

1

1

–

1

1

–

1

1

P002

1

1

–

1

1

–

0

P003

2

1

1

0

1

1

0

0

P004

2

1

1

0

1

1

0

P005

2

1

1

0

1

1

0

P006

3

1

–

1

1

–

1

1

P007

4

1

1

1

1

1

1

1

P008

5

1

–

1

1

–

1

1

P009

5

0

–

0

0

–

0

P010

6

1

1

1

1

1

1

1

P011

6

1

1

1

1

1

1

P012

7

0

–

0

0

–

0

1

P013

8

1

1

1

1

1

1

1

P014

9

1

–

–

1

–

–

–

P015

10

1

–

1

1

–

1

1

P016

11

1

–

1

1

–

1

1

P017

12

1

–

1

1

–

1

1

P018

13

1

–

1

1

–

1

0

sensitivity/specificity

Ā 

0.889

1.000

0.706

0.888

1.000

0.647

0.833

MTLE-HS right

P019

14

–

–

–

–

–

–

1

P020

15

–

–

–

–

–

–

1

P021

16

–

–

–

–

–

–

1

P022

17

1

1

1

1

1

1

1

P023

18

1

–

1

1

–

1

1

P024

19

–

–

–

–

–

–

1

P025

20

0

–

–

0

–

–

–

P026

21

1

–

–

1

–

–

–

P027

22

1

–

0

0

–

0

0

P028

23

1

–

–

1

–

–

–

sensitivity/specificity

Ā 

0.833

1.000

0.667

0.667

1.000

0.667

0.857

LTLE left

P029

24

–

–

0

–

–

0

–

P030

25

–

0

0

–

0

0

–

P031

25

–

0

0

–

0

0

P032

26

–

–

–

–

–

–

–

P033

27

1

–

1

0

–

1

0

P034

27

1

–

1

0

–

0

P035

27

0

–

0

0

–

0

P036

28

0

–

0

0

–

0

1

P037

29

1

–

–

1

–

–

–

P038

30

–

–

1

–

–

1

–

sensitivity/specificity

Ā 

0.600

0.000

0.375

0.200

0.000

0.250

0.500

LTLE right

P039

31

1

–

0

0

–

0

0

P040

32

0

0

0

0

0

0

0

P041

32

1

0

1

1

0

1

P042

33

1

1

–

1

1

–

–

P043

33

1

1

–

1

1

–

P044

34

–

–

0

–

–

0

–

P045

35

0

–

–

0

–

–

–

P046

36

–

–

0

–

–

0

–

P047

37

1

–

1

1

–

1

1

sensitivity/specificity

Ā 

0.714

0.500

0.333

0.571

0.500

0.333

0.333

overall sensitivity/specificity

Ā 

0.806

0.714

0.559

0.694

0.714

0.500

0.750

  1. Morphometric findings were counted as sensitive if at least one detection with Lr ≄ 2 (equation (2) in the Methods section) was consistent with a lesional finding by expert MRI reading, the surgical resection in case of favorable outcome (Engel class I and II) and follow-up for at least six months, or lateralizing signs in expert EEG reading. More strictly, morphometry was counted as specific if any of the three most prominent detections with Lr ≄ 2 was consistent. Overall sensitivities and specificities were calculated as the fraction of consistent datasets in all lesional MRIs, in all datasets with subsequent surgery or in all datasets with focal EEG, respectively.
  2. Matches are indicated by ā€œ1ā€ and disagreement by ā€œ0ā€. The dash indicates that information was not available or not applicable.