Table 3 Association of the relative abundance of single gut bacteria with clinical domains in hospitalized patients. Significant correlations between relative abundance of specific taxa of gut microbiota, identified by 16S rRNA microbial profiling analyses, and clinical parameters (number of drugs, Rockwood Clinical Frailty Scale and CIRS Comorbidity Score) at multivariate linear regression models. Taxa identified in the gut microbiota but lacking any significant correlation with the considered clinical parameters are not shown, but are fully listed in Supplemental Material.
From: Gut microbiota composition is associated with polypharmacy in elderly hospitalized patients
Taxa | Number of drugs | Rockwood Clinical Frailty Scale | CIRS Comorbidity Score | |||
|---|---|---|---|---|---|---|
Beta ± SE | p* | Beta ± SE | p** | Beta ± SE | p*** | |
Asteroleplasma | 0.0008 ± 0.00004 | 0.03 | — | — | — | — |
Bradyrhizobium | 0.000002 ± 0.0000001 | 0.02 | — | — | — | — |
Coprobacter | 0.0005 ± 0.0002 | 0.04 | — | — | — | — |
Enterobacter | — | — | — | — | 0.00003 ± 0.00001 | 0.02 |
Fonticella | — | — | 0.0009 ± 0.0004 | 0.04 | — | — |
Gordonibacter | 0.00003 ± 0.00001 | 0.04 | — | — | — | — |
Helicobacter | 0.0005 ± 0.00002 | 0.003 | — | — | — | — |
Massilia | −0.000007 ± 0.000003 | 0.04 | — | — | — | — |
Morganella | — | — | — | — | 0.00004 ± 0.00001 | 0.004 |
Oscillospira | — | — | 0.0005 ± 0.00002 | 0.02 | — | — |
Parabacteroides | 0.003 ± 0.001 | 0.02 | — | — | — | — |
Peptococcus | — | — | 0.00001 ± 0.000006 | 0.02 | — | — |
Porphyromonas | — | — | 0.0001 ± 0.00005 | 0.02 | — | — |
Prevotella | 0.003 ± 0.0001 | 0.01 | 0.00001 ± 0.000006 | 0.02 | — | — |
Pantoea | — | — | — | — | 0.0002 ± 0.00008 | 0.008 |
Roseburia | — | — | — | — | −0.00003 ± 0.00001 | 0.02 |
Scardovia | — | — | — | — | 0.00002 ± 0.000008 | 0.003 |
Shuttleworthia | — | — | — | — | −0.002 ± 0.001 | 0.04 |
U. m. of candidate division TM7 phylum | — | — | — | — | 0.000001 ± 0.000001 | 0.01 |
U. m. of Bacilli class | −0.00004 ± 0.000001 | 0.02 | — | — | — | — |
U. m. of Clostridiaceae 1 family | — | — | 0.00003 ± 0.00001 | 0.04 | — | — |
U. m. of Lachnospiraceae family | −0.13 ± 0.006 | 0.03 | 0.01 ± 0.006 | 0.04 | — | — |
U. m. of Ruminococcaceae family | 0.005 ± 0.002 | 0.02 | — | — | — | — |
U. m. of Clostridia class | — | — | — | — | 0.000003 ± 0.000002 | 0.05 |
U. m. of Erysipelotrichiaceae family 1 | — | — | — | — | −0.0007 ± 0.00004 | 0.05 |
U. m. of Erysipelotrichiaceae family 2 | — | — | — | — | 0.00004 ± 0.00001 | <0.001 |
U. m. of A0839 family | 0.0001 ± 0.00004 | 0.01 | — | — | — | — |
U. m. of Desulfovibrionaceae family | 0.000001 ± 0.0000001 | 0.01 | — | — | — | — |
U. m. of Succinivibrionaceae family | −0.000006 ± 0.0000003 | 0.05 | — | — | — | — |
Victivallis | 0.00006 ± 0.00003 | 0.04 | — | — | — | — |
