Figure 7
From: The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy
SIRT6-KO mice show degenerative muscle phenotype. Representative sections of gastrocnemius muscles from WT (A,D,F) and SIRT6-KO (B,E,G) mice stained with hematoxylin-eosin stains to visualize fiber size (A,B) and to analyze cross-sectional diameter (C) of muscle fibers. (D, E) Infiltration of inflammatory cells and (F,G) position of nuclei (arrow) in the muscle fibers. Scale bars are as indicated. Data represented as mean ± SEM, n = 3, *p < 0.05.
