Table 2 MIC values of DLP2 and DLP4 against bacteria.

From: Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus

Species and strains

MIC

DLP2

DLP4

Vancomycin

Ciprofloxacin

μM

μg/ml

μM

μg/ml

μM

μg/ml

μM

μg/ml

Gram-positive bacteria

Staphylococcus aureus ATCC25923a

0.01

0.031

0.01

0.062

0.04

0.062

0.08

0.031

S. aureus ATCC43300a

0.12

0.5

0.23

1.0

0.69

1.0

5.44

2.0

S. aureus ATCC6538a

0.12

0.5

0.47

2.0

NT

NT

NT

NT

S. aureus CICC546c

0.23

1.0

0.47

2.0

0.35

0.5

2.72

1.0

Streptococcus suis CVCC606b

0.93

4.0

1.88

8.0

0.01

0.015

0.045

0.015

Listeria ivanovii ATCC19119a

0.12

0.5

0.12

0.5

0.35

0.5

1.36

0.5

Gram-negative bacteria

Escherichia coli CVCC1515b

>29.97

>128

>29.98

>128

44.17

64

0.04

0.016

E. coli CICC21530 (serotype O157:H7)c

>29.97

>128

>29.98

>128

44.17

64

0.04

0.016

Salmonella typhimurium ATCC14028a

>29.97

>128

>29.98

>128

>88.34

>128

0.04

0.016

S. enteritidis CMCC50336d

>29.97

>128

>29.98

>128

>88.34

>128

0.04

0.016

  1. Note: NT: not test. aAmerican Type Culture Collection (ATCC); bChina Veterinary Culture Collection Center (CVCC); cChina Center of Industrial Culture Collection (CICC); dNational Center Center for Medical Culture Collection (CMCC). Data were representative of three independent experiments.