Figure 7
Monitoring the 3Cpro activity of CVA9, poliovirus, and CVB3 infection via HEK293T-i-3CS-GLuc2 cells. HEK293T-i-3CS-GLuc2 cells were infected with the CVA9 Griggs strain, the poliovirus vaccine strain Sabin 3, and the CVB3 Nancy strain at an MOI of 0.5 respectively. At 24 hours post infection, cells were harvested and subjected to luciferase assays. The results are presented as the means ± SD of triplicate measurements (Student’s t test; ***p < 0.001, ****p < 0.0001).
