Figure 8 | Scientific Reports

Figure 8

From: Alcohol amplifies ketamine-induced apoptosis in primary cultured cortical neurons and PC12 cells through down-regulating CREB-related signaling pathways

Figure 8

ALC potentiates KET-induced down-regulation of CaMK-IV and up-regulation of cleaved caspase-3 and Bax expression. Representative immunoblots (a) and quantitative analysis of CaMK-IV (b), cleaved caspase-3/caspase-3 (c) and Bax (d). The gels have been run under the same experimental conditions. The histogram in each panel indicated the relative band intensity generated from densitometric scans of three independent experiments. *p < 0.05, **p < 0.01 compared with the control group. # p < 0.05, ## p < 0.01 compared with the group treated with ALC and KET. $ p < 0.05 compared with the group treated with ALC.

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