Figure 4 | Scientific Reports

Figure 4

From: Host immune status-specific production of gliotoxin and bis-methyl-gliotoxin during invasive aspergillosis in mice

Figure 4

The kinetics of GT and bmGT accumulation in the A. fumigatus-infected lung varies depending on the underlying host risk factor. p47 phox−/− CGD, hydrocortisone-treated, and neutropenic mice were infected with A. fumigatus and euthanized at day 1, 3 and 5 post-infection for determination of GT and bmGT levels using HPLC. Shown are levels of GT (A), bmGT (B) and the bmGT/GT ratio (C) in mouse lungs. * P < 0.05; ** P < 0.01. Data represent the mean ± SEM. Two independent experiments were performed with similar results with a total of 3–6 mice per time-point.

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