Table 2 Estimated means and difference in estimated means (at t = 0 and time trend) between exacerbation and control group based on linear mixed-effects modela.

From: Early detection of pulmonary exacerbations in children with Cystic Fibrosis by electronic home monitoring of symptoms and lung function

  

Estimated means (SE)

Estimated mean difference (95%CI)

T = −4

T = −2

T = 0

T = 0

p

Time trend

p

FEV1%pred

E group

69.33 (11.52)

68.58 (11.37)

67.82 (11.30)

−16.30 (−28.75, −3.85)

0.012

0.067 (−0.232, 0.366)

0.650

NE group

87.51 (12.61)

85.81 (12.25)

84.12 (12.15)

RSS

E group

2.25 (1.38)

2.76 (1.35)

3.27 (1.33)

2.97 (1.52, 4.42)

<0.001

0.051 (0.000, 0.102)

0.051

NE group

0.70 (1.54)

0.50 (1.46)

0.30 (1.43)

  1. Abbreviations: E, exacerbation; NE, no exacerbation; FEV1% predicted, forced expiratory volume in 1 second percentage of predicted; RSS, Respiratory Symptom Score. aReference categories: site University Medical Centre Utrecht, female sex, age 10.3 years, exacerbations in 2 years before inclusion, Pseudomonas Aeruginosa at inclusion, season autumn.