Figure 12 | Scientific Reports

Figure 12

From: Identification and Validation of a PD-L1 Binding Peptide for Determination of PDL1 Expression in Tumors

Figure 12

RK-10-Cy5 detects presence of PD-L1 on Reed-Sternberg cells in Hodgkin’s Lymphoma. Hodgkin’s Lymphoma tissues were incubated with either fluorescent RKC-10-Cy5 peptide (a–c) or SP263 antibody (d) to examine PD-L1 levels in Reed-Sternberg (RS) cells. RKC-10-Cy5 was able to specifically stain the RS cells (some but not all indicated by arrows), which are known to express high levels of PD-L1. PD-L1 expression in RS cells was also confirmed with the SP263 staining.

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