Table 2 Comparison of the genotype and allele frequencies of the SRGAP2 SNPs in the Han and Maonan populations [n (%)]. HWE, Hardy-Weinberg equilibrium. n = sample size.
From: The SRGAP2 SNPs, their haplotypes and G × E interactions on serum lipid traits
Group | n | Genotype | Allele | |||
|---|---|---|---|---|---|---|
rs2483058 | GG | GC | CC | G | C | |
Han | 1210 | 514 (42.48) | 495 (40.90) | 201 (16.62) | 1523 (62.93) | 897 (37.07) |
Maonan | 1234 | 421 (34.12) | 593 (48.06) | 220 (17.82) | 1435 (58.14) | 1033 (41.86) |
x 2 | 18.701 | 11.731 | ||||
P | 9E-005 | 0.001 | ||||
P HWE | 0.357 | |||||
Han | ||||||
Male | 465 | 216(46.45) | 183(39.35) | 66(14.20) | 615(66.13) | 315(33.87) |
Female | 745 | 298(40.00) | 312(41.88) | 135(18.12) | 908(60.94) | 582(39.06) |
x 2 | 5.910 | 6.610 | ||||
P | 0.052 | 0.010 | ||||
P HWE | 0.423 | |||||
Maonan | ||||||
Male | 500 | 151(30.20) | 243(48.60) | 106(21.20) | 545(54.50) | 455(45.50) |
Female | 734 | 270(36.78) | 350(47.68) | 114(15.54) | 890(60.63) | 578(39.37) |
x 2 | 9.192 | 9.174 | ||||
P | 0.010 | 0.002 | ||||
P HWE | 0.566 | |||||
rs2580520 | ||||||
Han | 1210 | 89(7.36) | 419(34.64) | 702(58.01) | 597(24.67) | 1823(75.33) |
Maonan | 1234 | 73(5.91) | 509(41.25) | 652(52.84) | 655(26.54) | 1813(73.46) |
x 2 | 11.921 | 2.243 | ||||
P | 0.003 | 0.134 | ||||
P HWE | 0.529 | |||||
Han | ||||||
Male | 465 | 23(4.94) | 158(33.98) | 284(61.08) | 204(21.94) | 726(78.06) |
Female | 745 | 66(8.86) | 261(35.03) | 418(56.11) | 393(26.38) | 1097(73.62) |
x 2 | 7.269 | 6.075 | ||||
P | 0.026 | 0.014 | ||||
P HWE | 0.448 | |||||
Maonan | ||||||
Male | 500 | 26(5.20) | 211(42.20) | 263(52.60) | 263(26.30) | 737(73.70) |
Female | 734 | 47(6.41) | 298(40.60) | 389(52.99) | 392(26.70) | 1076(73.30) |
x 2 | 0.921 | 0.050 | ||||
P | 0.631 | 0.853 | ||||
P HWE | 0.772 | |||||
