Table 6 The SRGAP2 rs2483058C-rs2580520G haplotype and hyperlipidemia in the Han and Maonan populations according to stratified risk factors.
From: The SRGAP2 SNPs, their haplotypes and G × E interactions on serum lipid traits
Factor | Type | Haplotype | OR (95%CI)Han | P Han | OR (95%CI)Maonan | P Maonan |
|---|---|---|---|---|---|---|
Gender | Male | C-G non-carriers | 1 | — | 1 | — |
Female | C-G carriers | 1.88 (1.33–2.66) | <0.001 | 1.24 (0.95–1.62) | <0.001 | |
BMI | <24 Kg/m2 | C-G non-carriers | 1 | — | 1 | — |
≥24 Kg/m2 | C-G carriers | 1.57 (1.23–2.02) | <0.001 | 1.26 (0.83–1.91) | 0.001 | |
Smoking | Nonsmoker | C-G non-carriers | 1 | — | 1 | — |
Smoker | C-G carriers | 1.25 (0.99–1.58) | 0.003 | 3.01 (1.77–5.11) | <0.001 | |
Drinking | Nondrinker | C-G non-carriers | 1 | — | 1 | — |
Drinker | C-G carriers | 0.88 (0.64–1.72) | 0.877 | 1.01 (0.92–1.23) | 0.654 | |
Diabetes | Non-diabetes | C-G non-carriers | 1 | — | 1 | — |
Diabetes | C-G carriers | 1.46 (1.16–1.86) | <0.001 | 1.53 (0.96–2.51) | 0.002 | |
Blood pressure | Normotensive | C-G non-carriers | 1 | — | 1 | — |
Hypertension | C-G carriers | 1.40 (0.85–2.05) | <0.001 | 1.68 (1.22–2.31) | <0.001 |
