Table 8 Correlation between serum lipid parameters and the SRGAP2 alleles/genotypes in the Han and Maonan populations.

From: The SRGAP2 SNPs, their haplotypes and G × E interactions on serum lipid traits

Lipid

SNP

Allele

Genotype

Std.error

Beta

t

P

Han plus Maonan

TC

rs2580520

 

GG/GC/CC

0.029

0.116

4.531

7.6E-004

HDL-C

rs2483058

 

GG/GC/CC

0.002

−0.139

−4.903

6.1E-004

 

rs2483058

G/C

 

0.033

0.111

3.978

9.5E-004

ApoA1

rs2483058

 

GG/GC/CC

0.091

0.091

3.443

0.001

ApoA1/ApoB

rs2483058

 

GG/GC/CC

0.013

−0.067

−3.048

0.002

 

rs2483058

G/C

 

0.001

−0.071

−2.993

0.003

Han

HDL-C

rs2483058

 

GG/GC/CC

0.028

−0.081

−2.422

0.016

 

rs2483058

G/C

 

0.054

0.054

2.718

0.044

ApoA1

rs2483058

 

GG/GC/CC

0.008

−0.136

−4.082

8.1E-004

Maonan

TC

rs2580520

 

GG/GC/CC

0.056

0.081

2.455

0.014

 

rs2580520

G/C

 

0.095

0.109

2.439

0.015

HDL-C

rs2483058

 

GG/GC/CC

0.017

−0.074

−2.430

0.015

ApoA1

rs2483058

 

GG/GC/CC

0.008

−0.103

−3.248

0.001

  1. TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; Apo, apolipoprotein; Beta, standardized coefficient. Association of serum lipid traits and allele and genotypes in Maonan, Han and combined the Maonan and Han populations were assessed by multivariable linear regression analyses with stepwise modeling.