Figure 5 | Scientific Reports

Figure 5

From: Penicilliumin B, a novel sesquiterpene methylcyclopentenedione from a deep sea-derived Penicillium strain with renoprotective activities

Figure 5

Penicilliumin B (1) inhibits fibrogenic action of high glucose in RMC cells. RMC cells were incubated with D-glucose (25 mM) for 48 h in the absence or presence of different concentrations (0.1, 0.5 μM) of 1. Cell lysates after various treatments as indicated were immunoblotted with antibodies against fibronectin, collagen I and α-tubulin (A). Full-length blots are presented in Supporting Information Figure S2. Graphic presentations of fibronectin (B) and collagen I (C) protein expressions in four groups as indicated. *p < 0.05 vs control (n = 3). †p < 0.05 vs HG alone (n = 3).

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