Figure 7

Penicilliumin B (1) suppresses oxidative stress in RMC cells. RMC cells were incubated with D-glucose (25 mM) for 24 h in the absence or presence of 1 (0.5 μM). NAPDH oxidase subunits of Nox4 and p47phox were analyzed by western blotting (A). Full-length blots are presented in Supporting Information Figure S4. Graphic presentations of Nox4 (B) and p47phox (C) protein expressions in three groups as indicated. *p < 0.05 vs control (n = 3). † p < 0.05 vs HG alone (n = 3).