Figure 7

Effect of DHC on the inflammatory pathway through down-regulating NO production, NF-κB (p65 subunits), and MMP-9 level. (A) NO production is shown as % of control after 24 h of reperfusion. (B) Representative of western blot analysis of MMP-9 and p65 in cerebral I/R rats at 24 h after reperfusion. Quantitative analysis of protein expressions of MMP-9 and p65 normalized using β-actin. (C) Representative of western blot analysis of TRPV1 in cerebral I/R rats at 24 h after reperfusion. Quantitative analysis of protein expressions of TRPV1 normalized using β-actin. The data are the mean ± S.E.M from three independent experiments (^** p < 0.01 and ^*** p < 0.001 compared with the sham group; and ^# p < 0.05 and ^## p < 0.01 compared with the vehicle group).