Table 2 Patients’ clinical and demographic characteristics and findings on SSC, FAS, and CAT.

From: Silent Sentence Completion Shows Superiority Localizing Wernicke’s Area and Activation Patterns of Distinct Language Paradigms Correlate with Genomics: Prospective Study

Age, years

Sex

Handedness

Tumor location

Histology/grade

SSC

FAS

CAT

Genetic markers

36

F

R

L frontal

GBM/4

Positive

Negative

Negative

p53, EGFR, PTEN IHC+

32

M

R

L parietal

Oligo-dendroglioma/3

Positive

Negative

Negative

1p19q co-deletion, EGFR IHC+, IDH1 exon 4 mutation

67

M

R

L frontal

GBM/4

Positive

Positive

Positive

EGFR IHC+

54

F

L

L parietal

GBM/4

Positive

Positive

Negative

EGFR IHC+

51

M

R

L insula

Anaplastic oligo-dendroglioma/3

Positive

Positive

Positive

1p/19q co-deletion, IDH1 (R132H) IHC+

53

M

R

L posterior temporal

GBM/4

Positive

Negative

Negative

p53 IHC+, EGFR IHC+

18

F

R

L frontal

Mixed oligo-astrocytoma/3

Positive

Negative

Negative

IDH1 (R132H) IHC+, EGFR, PTEN IHC+

69

F

R

L inferior temporal

GBM/4

Positive

Negative

Negative

EGFR IHC+, MGMT promoter methylation

50

M

M

L frontal + temporal

GBM/4

Positive

Negative

Negative

p53 IHC+

37

M

R

L temporal

Oligo-dendroglioma/3

Positive

Negative

Negative

IDH1 exon 4 mutation, 1p/19q co-deletion

65

F

R

L parietal + angular gyri

GBM/4

Positive

Negative

Negative

EGFR IHC+, PTEN loss of wild-type expression

45

M

R

L insula + frontal operculum

GBM/4

Positive

Negative

Negative

None

19

M

R

L parietotemporal

GBM /4

Positive

Negative

Negative

TP53 exon 8 mutation, IDH1 exon 4 mutation

33

M

R

L frontal, + L insula, + L temporal

Oligo-dendroglioma/3

Positive

Negative

Negative

1p/19q co-deletion, IDH1 (R132H) IHC+

18

F

R

R frontal + L frontal

Oligo-dendroglioma/2

Positive

Negative

Negative

1p/19q co-deletion, IDH1 (R132H) IHC+

39

M

M

R insula, frontal, + temporal

Oligo-dendroglioma/2

Positive

Negative

Negative

1p/19q co-deletion, IDH1 (R132H) IHC+

62

M

M

R frontal + insula

GBM/4

Positive

Negative

Negative

p53 IHC+

52

M

R

L caudate nucleus, internal capsule, + L temporal

GBM/4

Positive

Negative

Negative

p53 IHC+

43

M

R

L frontal

Astrocytoma/2

Positive

Positive

Positive

IDH (R132H) IHC+, p53 IHC+

43

M

L

R parietal

GBM/4

Positive

Negative

Negative

p53, S-100 IHC+

51

F

R

L frontotemporal

GBM/4

Positive

Negative

Negative

S100 IHC+

51

F

R

L frontal, insula, +anterior temporal

GBM/4

Positive

Negative

Negative

TP53 exon 7 mutation

28

F

L

L frontal

Astrocytoma/3

Positive

Positive

Positive

IDH-1 R132H) IHC+, EGFR IHC+

50

M

R

R + L frontal

GBM/4

Positive

Positive

Positive

p53, PTEN, EGFR IHC+

31

F

R

Superior L temporal

Ganglioglioma/2

Positive

Negative

Negative

None

62

M

L

L temporal

GBM/4

Positive

Negative

Negative

PTEN, EGFR, P53 IHC+

54

M

R

R frontal + L temporal

GBM/4

Positive

Negative

Negative

p53 IHC+

35

M

L

R occipito-temporal + bifrontal

Astrocytoma/3

Positive

Negative

Negative

IDH-1 (R132H) IHC+

25

F

R

R frontal

Oligo-dendroglioma/2

Positive

Positive

Positive

1p/19q co-deletion,IDH-1 (R132H) IHC+

35

M

R

L posterior temporal

Oligo-dendroglioma

Positive

Positive

Negative

None

49

F

R

L temporal

Oligo-dendroglioma

Positive

Positive

Negative

1p/19q, IDH-2 p.515 G > A IHC+

18

M

R

L temporal

Astrocytoma

Positive

Negative

Negative

p53 IHC+

33

M

R

R superior, middle, +inferior frontal gyri

Astrocytoma

Positive

Positive

Positive

IDH1 (R132H) IHC+

48

M

R

L frontal

Diffuse glioma

Positive

Positive

Positive

IDH1 (R132H) IHC+, 1p/19q co-deletion

32

F

M

L frontal

Astrocytoma

Positive

Negative

Negative

IDH1 (R132H) IHC+

  1. R: right, L: left, IHC: Immunohistochemistry, GBM: glioblastoma.