Table 2 Particle size, polydispersity index (PI), drug loading (DL), and encapsulation efficiency (EE) of trans-resveratrol (t-Rev)-loaded self-assembling lecithin-based mixed polymeric micelles (saLMPMs) formed using t-Rev, lecithin, and PP123 in various ratios.
Rev:L:PP123 | Particle size (nm) | P.I. | D.L. (%) | E.E. (%) |
|---|---|---|---|---|
1:0:5 | 104.4 ± 2.63 | 0.217 ± 0.064 | 14.12 | 84.74 |
1:1:5 | 145.6 ± 1.42 | 0.578 ± 0.007 | 11.81 | 82.66 |
1:0:10 | 75.4 ± 2.1 | 0.564 ± 0.148 | 5.38 | 59.15 |
1:1:10 | 203.8 ± 76.15 | 1.231 ± 0.318 | 7.45 | 89.35 |
3:1:10 | 129 ± 8.47 | 0.289 ± 0.119 | 17.25 | 80.51 |
3:2:10 | 153.6 ± 35.44 | 0.989 ± 0.31 | 17.38 | 86.90 |
1:0:20 | 24.3 ± 0.88 | 1.465 ± 0.211 | 4.77 | 100.18 |
1:1:20 | 104.6 ± 4.34 | 1.595 ± 0.025 | 4.75 | 104.54 |
4:1:20 | 102.8 ± 3.81 | 0.754 ± 0.046 | 14.86 | 92.86 |
5:1:20 | 112.6 ± 9.2 | 0.3 ± 0.24 | 18.69 | 97.17 |
5:2:20 | 147.7 ± 9.62 | 0.842 ± 0.076 | 18.52 | 103.93 |