Table 2 Particle size, polydispersity index (PI), drug loading (DL), and encapsulation efficiency (EE) of trans-resveratrol (t-Rev)-loaded self-assembling lecithin-based mixed polymeric micelles (saLMPMs) formed using t-Rev, lecithin, and PP123 in various ratios.

From: Physical and Pharmacokinetic Characterizations of trans-Resveratrol (t-Rev) Encapsulated with Self-Assembling Lecithin-based Mixed Polymeric Micelles (saLMPMs)

Rev:L:PP123

Particle size (nm)

P.I.

D.L. (%)

E.E. (%)

1:0:5

104.4 ± 2.63

0.217 ± 0.064

14.12

84.74

1:1:5

145.6 ± 1.42

0.578 ± 0.007

11.81

82.66

1:0:10

75.4 ± 2.1

0.564 ± 0.148

5.38

59.15

1:1:10

203.8 ± 76.15

1.231 ± 0.318

7.45

89.35

3:1:10

129 ± 8.47

0.289 ± 0.119

17.25

80.51

3:2:10

153.6 ± 35.44

0.989 ± 0.31

17.38

86.90

1:0:20

24.3 ± 0.88

1.465 ± 0.211

4.77

100.18

1:1:20

104.6 ± 4.34

1.595 ± 0.025

4.75

104.54

4:1:20

102.8 ± 3.81

0.754 ± 0.046

14.86

92.86

5:1:20

112.6 ± 9.2

0.3 ± 0.24

18.69

97.17

5:2:20

147.7 ± 9.62

0.842 ± 0.076

18.52

103.93