Figure 3

Global annotated mt-variants in tumour lesions with different growth patterns (group I). Common mt-variants (intersection area), adaptive mt-polymorphisms and somatic mutants occurring in NSCLC tumour lesions of cases #01ā#06 are illustrated in Venn diagrams (A). Variants are shown according to their mt-genomic location and gene regions (B). Adaptive mt-polymorphisms common in all lesions of individual sample are labelled in green, whereas somatic mt-mutations with pathogenic impact on some lesions are shown in red (c.f. Supplemental Data and TableĀ S4).