Table 2 Reduced penetration of deltamethrin in resistant MRS versus susceptible Kisumu after topical application.

From: Contributions of cuticle permeability and enzyme detoxification to pyrethroid resistance in the major malaria vector Anopheles gambiae

Treatment

Sample bodies

ng/mosquito (SD)

p-value (Wilcoxon rank)

Deltamethrin

Kisumu

0.048 (0.026)

0.002 (W = 36)

MRS

0.007 (0.001)

PBO + Deltamethrin

Kisumu

0.066 (0.136)

0.006 (W = 36)

MRS

0.010 (0.023)

Dicyclohexyl phthalate

Kisumu

0.073 (0.039)

0.004 (W = 36)

MRS

0.006 (0.002)

  1. Three biological replicate pools of 40 mosquitoes per treatment were used for chemical analysis. Deltamethrin was determined using Gas Chromatography coupled to an Electron Capture Detector (GC-ECD), PBO and dicyclohexyl phthalate by Gas Chromatography with Mass Spectrometry (GC-MS). Dicyclohexyl phthalate was used as control since it has a similar structure to deltamethrin and is not metabolised by the insects. The figures represent the means with standard deviations (SD) of the chemical contents. ng = nanogram. p-value < 0.05 indicates a significant difference according to the Wilcoxon rank sum test.
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