Figure 1 | Scientific Reports

Figure 1

From: Very-Low-Density Lipoprotein of Metabolic Syndrome Modulates Gap Junctions and Slows Cardiac Conduction

Figure 1

Prolongation of P waves, PR intervals, QRS, and QT intervals along with Left atrial and left ventricular dilatation and comparable intra-cardiac fibrosis. (a) The dash lines indicate measurements of P wave width (P), PR interval (PR), QRS width, and QT interval. (b) P, PR, QRS, and QTc in MetS-VLDL injected mice (msVLDL), Normal-VLDL injected mice (nVLDL) and control mice (n = 10 for each) $P < 0.05; $P < 0.05. (c) Representative electrocardiographic tracings of unprovoked atrial fibrillation from two msVLDL mice. (d) B-mode and M-mode images for measurements of dimensions of aortic root (AO), left atria (LA), and left ventricles (LV). (e) LA size and LV end-diastolic dimension (msVLDL vs control, $P < 0.01; msVLDL vs nVLDL, #P < 0.01). (f) Gross morphology of hearts. The msVLDL atrium was larger than the control and nVLDL ones. (g) Histological sections of control, nVLDL, and msVLDL stained with Masson-Trichrome; black bars indicate 50 μm.

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