Figure 4
From: Sexual congruency in the connectome and translatome of VTA dopamine neurons
Translatome analysis of dopamine neurons in female and male mice. (A) Schematic demonstrating the injection of AAV1-FLEX-Rpl22-HA into the VTA of female and male Slc6a3 Cre mice. (B) mRNA levels are highly correlated between females and males. (C,D) Two genes, Xist (red, C) and Eif2s3y (blue, D) are highly differentially expressed in male and female mice. Xist is significantly enriched in dopamine neurons of female mice (C). (F) mRNA with a greater than 4-fold enrichment in dopamine neurons, including those necessary for dopamine synthesis and release (inset), are not different between females and males.
