Table 2 Noninvasive markers of liver disease.
From: Prevalence and predictors of liver disease in HIV-infected children and adolescents
Parameter | Total | HIV without HBV or HCV coinfection Group I | HIV with HBV or HCV coinfection Group II | P Group I vs. Group II | |
|---|---|---|---|---|---|
Number | 79 | 71 | 8 | ||
ALT (IU/L) | Median (IQR) | 25.0 (21.3–33.8) | 25.0 (21.0–31.0) | 70.5 (49.0–83.5) | <0.0001 |
AST (IU/L) | Median (IQR) | 29.0 (24.0–37.0) | 27.0 (23.0–35.0) | 49.0 (37.0–57.5) | 0.0004 |
Bilirubin (µmol/L) | Median (IQR) | 10.6 (7.4–14.9) | 10.7 (7.2–15.1) | 10.3 (8.9–12.9) | 0.94 |
GGTP (IU/L) | Median (IQR) | 24.0 (18.0–38.0) | 23.0 (18.7–35.0) | 74.5 (41.5–147.5) | 0.0002 |
APRI score | Mean ± SD | 0.28 (0.21–0.36) | 0.26 (0.20–0.33) | 0.57 (0.40–0.75) | 0.0001 |
>0.5 | 4 (5) | 0 | 4 (50) | <0.0001 | |
>1.5 | 1 (1) | 0 | 1 (13) | 0.1 | |
FIB-4 | Mean ± SD | 0.30 (0.21–0.43) | 0.29 (0.19–0.41) | 0.50 (0.40–0.60) | 0.0025 |
>1.45 | 1 (1) | 0 | 1 (13) | 0.1 | |
