Figure 1
Moderating effect of sex. (a) An illustration of the right (yellow) and left (cyan) amygdala-vPFC pathway masks, defined using probabilistic tractography data from an independent group of samples (n = 71)13. (b) The association between the right amygdala-vPFC pathway strength and trait anxiety was significantly moderated by sex. (c) The same moderating effect of sex was observed for the left amygdala-vPFC pathway. Both p-values were below the FDR-corrected threshold of q < 0.05. (d,e) Significant inverse correlations between the right amygdala-vPFC pathway strength and trait anxiety were observed in women but not men. (f,g) The same effect was found in the left amygdala-vPFC pathway. All p-values were below the FDR-corrected threshold of q < 0.05. Correlation coefficients were calculated controlling for the effects of age and head motion.
