Figure 1
From: Microbial communities in placentas from term normal pregnancy exhibit spatially variable profiles
Microbial community profiles in normal term placentas are spatially distinct based on absolute abundance of the 16S gene and alpha-diversity. (A) Schematic of the gestational compartment depicting the maternal side (BP) and fetal side (PV and FM). (B) Copy numbers/µL of validated V4 samples are plotted per sample type—BP (N = 21), PV (N = 13), FM (N = 16), Blank (N = 8), Water (N = 9). Samples above the dotted threshold (>34 Copies/µL) indicate samples that have met stringency filter set at the maximum copy number/uL of the negative controls (BP vs. FM–P = 0.04; BP vs. PV–0.66; FM vs. PV–P = 0.98; Blanks vs. Water–P = 0.17). (C) Shannon diversity score of validated samples grouped by sampling location (FM vs. BP: P = 0.01, PV vs. BP: P = 0.94, PV vs. FM: P = 0.07). Statistical analyses were performed using Mann-Whitney and significant differences are designated with the following annotations: P = *>0.05, *<0.005, *<0.0005.
