Figure 6 | Scientific Reports

Figure 6

From: Impact of mitochondrial nitrite reductase on hemodynamics and myocardial contractility

Figure 6

(A,B) Intracellular effects contributing to hemodynamic parameters assessed by NO-Hb formation and cGMP synthesis in different cell cultures. Contribution of nitrite (30 µM, final concentration), myxodiazol (Myxo) and potassium cyanide (KCN) on NO-Hb formation in cell cultures of red blood cells (RBCs) and cardiomyocyte (HL-1) (A). Contribution of SNAP, nitrite, myxodiazol (Myxo) and potassium cyanide (KCN) on cGMP formation in cell cultures of RBCs and cardiomyocyte (HL-1) (B). Controls are displayed with open bars. Data are expressed as mean ± SEM of three independent experiments with 4 replicates each, *p < 0.05, ***p < 0.001.

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