Table 2 Backpressures and flow rates through the Tangential Flow Filter (TFF) that were investigated in this study.

From: Formation and purification of tailored liposomes for drug delivery using a module-based micro continuous-flow system

Backpressure (psi)

7

15

23

31

39

49

50

59

62

75

80

Flow rate (mL min−1)

0.01

0.02

0.03

0.1

0.05

1

0.3

2

2.5

0.5

0.1

Capillary I.D. (μm)

50

50

50

63

50

100

63

100

100

63

50

Capillary length (mm)

50

50

50

50

50

50

25

30

25

25

50

  1. Liposomes in solution were fed into the TFF device at flow rates ranging between 0.01 and 2.5 mL min−1. Backpressure was attained by connecting a restrictive capillary with selected (I.D.) and/or length on the retentate side of the TFF outlet.
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