Figure 1
Histopathological features of the PAS-stained kidney sections originating either from MCD-diagnosed patients (a,b) or healthy control subjects (c,d). No major morphological differences between the groups could be noticed. The confocal laser scanning micrographs of nephrin-stained sections of MCD patients (e,f) or control kidneys (g,h) show a slightly weaker staining for nephrin in the MCD-diagnosed patient biopsies (e,f). The appearance of single nephrin-positive SDs can be distinguished (f, inset). G exemplarily indicates encircled glomeruli, which are magnified in the following pictures. The scale bars indicate in (c) 100 µm, in (d) 40 µm, in (g) 40 µm and in (h) 10 µm.
