Figure 6
From: The parathyroid hormone regulates skin tumour susceptibility in mice
The expressions of cell-differentiation markers are elevated in dorsal back skin of Pth MSM-Tg mice. (a,b) Dorsal back skin HE sections of 8-week-old littermates (n = 5) (a) and Pth MSM-Tg mice (n = 5) (b) are shown. (c–f) Representative immunostaining patterns of anti-Loricrin antibody (Lor) (c,d) and anti-Kratin10 antibody (Krt10) (e,f) positive cells (red) in the skin from control littermates (c,e) and Pth MSM-Tg mice (d,f). Cells were counterstained with DAPI (blue). (g–i) The mRNA expression levels of Lor (g), Flg (h) and Krt10 (i) are shown for each littermate (red) and Pth MSM-Tg mouse (blue) at the age of 2 months. The Lor, Flg and Krt10 transcript levels are shown relative to the transcript levels of Gapdh. The P-values were calculated by t-test (*P < 0.05, **P < 0.01, and ***P < 0.001). (g–i) Error bars are standard deviation (SD). Asterisks indicate significant differences. Horizontal bold lines indicate mean values. Each dot indicates each experiment. Scale bars, 100 μm.
