Figure 2

Effects of Sul 121 treatment on glomerular histology. Representative pictures of PAS stainings are shown for lean vehicle (A), lean Sul-121 (B), db/db vehicle (C) and db/db Sul-121 (D). Inserts show details of glomerular staining. (E) Glomerular size was increased in db/db vehicle and normalized in db/db Sul-121. (F) Glomerulosclerosis scores were increased in db/db vehicle and significantly reduced in db/db Sul-121. *p < 0.05 db/db vehicle vs lean vehicle, #p < 0.05 db/db Sul-121 vs db/db vehicle.